Publications

359. Humanized anti-DEspR IgG4S228P Antibody Increases Overall Survival in a Pancreatic Cancer Stem Cell-xenograft Peritoneal Carcinomatosis Ratnu/nu Model.
Christopher M. Gromisch, Glaiza L.A. Tan, Kristine A. Pasion, Matthew S. Gromisch, Mark W. Grinstaff, Francis J. Carr, Victoria L.M. Herrera, and Nelson Ruiz-Opazo
BMC Cancer, 2021, 21, 407.

358. The Prognosis of Arthrofibroses: Prevalence, Clinical Shortcomings, and Future Prospects.
William A. Blessing, Amanda K. Williamson, Jack R. Kirsch, and Mark W. Grinstaff
Trends in Pharmacological Sciences, 2021, 42, 398-415.

357. Controlled Cell Alignment Using Two-Photon Direct Laser Writing-Patterned Hydrogels in 2D and 3D.
Jiaxi Song, Christos Michas, Christopher S. Chen, Alice E. White, and Mark W. Grinstaff
Macromolecular Bioscience, 2021, in press.

356. Nanotechnology in Thoracic Surgery.
David A. Mahvi, Mark W. Grinstaff, and Yolonda L. Colson
Nanotechnology in Thoracic Surgery, Pearson’s General Thoracic, STS Cardiothoracic E-Book 2021.

355. Asah2 Represses the p53-Hmox1 Axis to Protect Myeloid-derived Suppressive Cells from Ferroptosis.
Huabin Zhu, John Klement, Chunwan Lu, Priscilla S. Redd, Dafeng Yang, lyssa D. Smith, Dakota B. Poschel, Juan Zou, Ding Liu, Peng George Wang, David Ostrov, Nicolas Coant, Yusuf A. Hannun, Aaron H. Colby, Mark W. Grinstaff, and Kebin Liu
The Journal of Immunology, 2021, 206, 1395-1404.

354. Quantitative Dual Contrast Photon-Counting Computed Tomography for Assessment of Articular Cartilage Health.
Petri Paakkari, Satu I. Inkinen, Miitu K. M. Honkanen, Mithilesh Prakash, Rubina Shaikh, Miika T. Nieminen, Mark W. Grinstaff, Janne T. A. Mäkelä, Juha Töyräs, and Juuso T. J. Honkanen
Scientific Reports, 2021, 11, 5556.

353. Implications for an Imidazol-2-yl Carbene Intermediate in the Rhodanese-Catalyzed C-S Bond Formation Reaction of Anaerobic Ergothioneine Biosynthesis.
Ronghai Cheng, Rui Lai, Chao Peng, Juan Lopez, Zhihong Li, Nathchar Naowarojna, Kelin Li, Christi-na Wong, Norman Lee, Stephen A. Whelan, Lu Qiao, Mark W. Grinstaff, Jiangyun Wang, Qiang Cui, and Pinghua Liu
ACS Catalysis, 2021, in press.

352. Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy (4th edition).
Daniel J. Klionsky, Amal Kamal Abdel-Aziz, Sara Abdelfatah, Mahmoud Abdellatif, Asghar Abdoli, Steffen Abel, Hagai Abeliovich, Marie H Abildgaard, Yakubu Princely Abudu, Abraham Acevedo-Arozena, Iannis E Adamopoulos…Mark W. Grinstaff… Orian S. Shirihai …Jialiu Zeng….Zhen Zou, Zhengzhi Zou, Steven Zuryn, and Werner Zwerschke
Autophagy, 2021, 1-404.

351. Irgm1 Links Mitochondrial Quality Control to Autoimmunity.
Prashant Rai, Kyathanahalli S. Janardhan, Julie Meacham, Jennifer H. Madenspacher, Wan-Chi Lin, Peer W.F. Karmaus, Jennifer Martinez, Quan-Zhen Li, Mei Yan, Jialiu Zeng, Mark W. Grinstaff, Orian S. Shirihai, Gregory A. Taylor, and Michael B. Fessler
Nature Immunology, 2021, 10.1038/s41590-020-00859-0.

350. Biofabrication of a Shape-Stable Auricular Structure for the Reconstruction of Ear Deformities.
Iris A. Otto, Pamela E. Capendale, João P. Garcia, Mylène de Ruijter, Rob F.M. van Doremalen, Miguel Castilho, Taylor Lawson, Mark W. Grinstaff, Corstiaan C. Breugem, Moshe Kon, Riccardo Levato, and Jos Malda
Materials Today Bio, 2021, 9, 100094.

349. Delivery of Eupenifeldin via Polymer-Coated Surgical Buttresses Prevents Local Lung Cancer Recurrence.
Zeinab Y. Al Subeh, Ngoc-Quynh Chu, Jeremy W. Miller, Lillian L. Tsai, Tyler N. Graf, Yin P. Hung, Cedric J. Pearce, Mark W. Grinstaff, Aaron H. Colby, Yolonda L. Colson, and Nicholas H. Oberlies
Journal of Controlled Release, 2021, 331, 260-269.

348. Regulation of Inflammatory and Catabolic Responses to IL-1β in Rat Articular Chondrocytes by microRNAs miR-122 and miR-451.
Kayla M. Scott, D. Joshua Cohen, Madeline Hays, Dane W. Nielson, Mark W. Grinstaff, Taylor B. Lawson, Brian D. Synder, Barbara D. Boyan, and Zvi Schwartz
Osteoarthritis and Cartilage, 2021, in press.

347. Cationic Contrast-enhanced Computed Tomography Distinguishes Between Reparative, Degenerative and Healthy Equine Articular Cartilage.
Brad B. Nelson, Janne T. A. Mäkelä, Taylor B. Lawson, Amit N. Patwa, Brian D. Snyder, C. Wayne McIlwraith, Mark W. Grinstaff, Laurie R. Goodrich, and Chris E. Kawcak
Journal of Orthopaedic Research, 2021, in press.

346. Nanotechnology and Osteoarthritis. Part 2: Opportunities for Advanced Devices and Therapeutics.
Taylor B. Lawson, Janne T.A. Mӓkelӓ, Travis Klein, Brian D. Snyder, and Mark W. Grinstaff
Journal of Orthopaedic Research, 2021, in press.

345. Nanotechnology and Osteoarthritis. Part 1: Clinical Landscape and
Opportunities for Advanced Diagnostics.
Taylor B. Lawson, Janne T.A. Mӓkelӓ, Travis Klein, Brian D. Snyder, and Mark W. Grinstaff
Journal of Orthopaedic Research, 2021, in press.

344. Effects of Human Articular Cartilage Constituents on Simultaneous Diffusion of Cationic and Non-ionic Contrast Agents.
Abhisek Bhattarai, Janne TA Mäkelä, Behdad Pouran, Harrie Weinans, Heikki
Kröger, Mark W. Grinstaff, Juha Töyräs, and Mikael J Turunen
Journal of Orthopaedic Research, 2021, in press.

343. Modulating Lysosomal pH: A Molecular and Nanoscale Materials Design Perspective
Jialiu Zeng, Orian Shirihai, and Mark W. Grinstaff
Journal of Life Sciences, 2020, 2, 25-37 (mentor-mentee mini review).

342. Breath Hold Enhances Regional Deposition of Aerosolized Droplets in a Reusable 3D Printed Bifurcating Airway Tree.
Adam Sonnenberg, Edward Taylor, Jarred Mondonedo, Samer Bou Jawde, Samir Amin, Jiaxi Song, Mark Grinstaff, and Béla Suki
Annals of Biomed Engineering, 2020, 10.1007/s10439-020-02623-9.

341. Hydrogel Embedded Quantum Dot-transcription Factor Sensor for Quantitative Progesterone Detection.
Mingfu Chen, Chloé Grazon, Prerana Sensharma, Thuy T. Nguyen, Yunpeng Feng, Margaret Chern, R C. Baer, Nitinun Varongchayakul, Katherine Cook, Sébastien Lecommandoux, Catherine M. Klapperich, James E. Galagan, Allison M. Dennis, and Mark W. Grinstaff
ACS Applied Materials & Interfaces, 2020, 12, 43513–43521.

340. Poly-Amido-Saccharides (PASs): Functional Synthetic Carbohydrate Polymers Inspired by Nature.
Anant S. Balijepalli and Mark W. Grinstaff
Accounts of Chemical Research, 2020, 53, 2167–2179.

339. Guidelines for β-Lactam Synthesis: Glycal Protecting Groups Dictate Stereoelectronics and [2+2] Cycloaddition Kinetics.
Anant S. Balijepalli, James H. McNeely, Aladin Hamoud, and Mark W. Grinstaff
Journal of Organic Chemistry, 2020, 85, 12044–12057.

338. A Markov Chain Model of Particle Deposition in the Lung.
Adam Sonnenberg, Jacob Herrmann, Mark W. Grinstaff, and Béla Suki
Nature Scientific Reports, 2020, 10, 13573.

337. Electrode Material-Ionic Liquid Coupling for Electrochemical Energy Storage.
Xuehang Wang, Maryam Salari, De-en Jiang, Jennifer C. Varela, Babak Anasori,
David J. Wesolowski, Sheng Dai, Mark W. Grinstaff, and Yury Gogotsi
Nature Reviews Material, 2020, 5, 787-808.

336. Surface Immobilized Nucleic Acid - Transcription Factor Quantum Dots for Biosensing.
Mingfu Chen, Thuy T. Nguyen, Nitinun Varongchayakul, Chloé Grazon, Margaret Chern, R C. Baer, Sébastien Lecommandoux, Catherine M. Klapperich, James E. Galagan, Allison M. Dennis, and Mark W. Grinstaff
Advanced Healthcare Materials, 2020, 2000403.

335. Single-step Replacement of an Unreactive C-H Bond by a C-S Bond Using
Polysulfide as the Direct Sulfur Source in Anaerobic Ergothioneine Biosynthesis.
Ronghai Cheng, Lian Wu, Rui Lai, Chao Peng, Nathchar Naowarojna, Weiyao Hu, Xinhao Li, Stephen A. Whelan, Norman Lee, Juan Lopez, Changming Zhao, Youhua Yong, Jiahui Xue, Xuefeng Jiang, Mark W. Grinstaff, Zixin Deng, Jiesheng Chen, Qiang Cui, Jiahai Zhou, and Pinghua Liu
ACS Catalysis, 2020, 10, 8981–8994.

334. Dual Contrast in Computed Tomography Allows Earlier Characterization of
Articular Cartilage Over Single Contrast.
Abhisek Bhattarai, Behdad Pouran, Janne T. A. Mäkelä, Rubina Shaikh, Miitu K.
M. Honkanen, Mithilesh Prakash, Heikki Kröger, Mark W. Grinstaff, Harrie
Weinans, Jukka S. Jurvelin, and Juha Töyräs
Journal of Orthopaedic Research, 2020, 38, 2230-2238.

333. Mega-Macromolecules as Single Molecule – Molecular Ball Bearings – Lubricants for Hard and Soft Surfaces.
Parambath Anilkumar, Taylor B. Lawson, Srinivas Abbina, Janne TA Mäkelä, Robert C. Sabatelle, Lily Takeuchi, Brian D. Snyder, Mark W. Grinstaff, and Jayachandran N Kizhakkedathu
Nature Communications 2020, 2139.

332. Pancreatic Adenocarcinoma: Unconventional Approaches for an Unconventional Disease.
Christopher Gromisch, Motaz Qadan, Mariana Albuquerque Machado, Kebin Liu, Yolonda L. Colson, and Mark W. Grinstaff
Cancer Research 2020, 80, 3179-3192.

331. A Novel Progesterone Biosensor Derived from Microbial Screening.
Chloé Grazon, R C. Baer, Uros Kuzmanovic, Thuy Nguyen, Mingfu Chen, Marjon Zamani, Margaret Chern, Patricia Aquino, Xiaoman Zhang, Sebastien Lecommandoux, Andy Fan, Mario Cabodi, Catherine Klapperich, Mark W. Grinstaff, Allison M. Dennis, and James Galagan
Nature Communications 2020, 1276.

330. Expansile Nanoparticles Encapsulate Factor Quinolinone Inhibitor 1 and Accumulate in Murine Liver upon Intravenous Administration.
Patrick Stoiber, Iriny Ekladious, Qing Zhao, Yolonda L. Colson, Scott E. Schaus, Ulla Hansen, and Mark W. Grinstaff
Biomacromolecules 2020, 21, 1499-1506.

329. Cationic Poly-Amido-Saccharides: Stereochemically-defined, Enantiopure Polymers from Anionic Ring-opening Polymerization of an Amino-Sugar Monomer.
Anant S. Balijepalli, Aladin Hamoud, and Mark W. Grinstaff
Polymer Chemistry 2020, 11, 1926-1936.

328. Paclitaxel-loaded Expansile Nanoparticles Improve Survival Following Cytoreductive Surgery in Pleural Mesothelioma Xenografts.
Rong Liu, Ngoc-Quynh Chu, Aaron Colby, Claire de Forcrand, Robert F. Padera, Mark W. Grinstaff, and Yolonda L. Colson
The Journal of Thoracic and Cardiovascular Surgery 2020, 160, e159-e168.

327. Verticillin A Causes Apoptosis and Reduces Tumor Burden in High Grade Serous Ovarian Cancer by Inducing DNA Damage.
Amrita Salvi, Chiraz Soumia M. Amrine, Julia R. Austin, KiAundra Kilpatrick, Angela Russo, Daniel D. Lantvit, Esther Calderon-Gierszal, Zachary Mattes, Cedric Pearce, Mark W. Grinstaff, Aaron H. Colby, Nicholas H. Oberlies, and Joanna E. Burdette
Molecular Cancer Therapeutics 2020, 19, 89-100.

326. Humidity-insensitive Tissue Oxygen Tension Sensing for Wearable Devices.
Emmanuel Rousakis, Juan Pedro Cascales, Haley L. Marks, Xiaolei Li, Mark W. Grinstaff, and Conor L. Evans
Photochemistry and Photobiology 2020, 96, 373-379.

325. Aqueous Ring-Opening Polymerization-Induced Self-Assembly (ROPISA) of N-carboxyanhydrides.
Chloé Grazon, Pedro Salas-Ambrosio, Emmanuel Ibarboure, Alix Buol, Elisabeth Garanger, Mark W. Grinstaff, Sébastien Lecommandoux, and Colin Bonduelle
Angewandte Chemie International Edition 2020, 59, 622-626.

324. A Synthetic Bioinspired Carbohydrate Polymer with Mucoadhesive Properties.
Anant S. Balijepalli, Robert C. Sabatelle, Mingfu Chen, Bela Suki, and Mark W. Grinstaff
Angewandte Chemie International Edition 2020, 59, 704-710.

323. dGEMRIC and CECT Comparison of Cationic and Anionic Contrast Agents in Intact Cadaveric Human Metacarpal Cartilage.
Jonathan D. Freedman, Daniel J. Ellis, Hrvoje Lusic, Gopal V. Varma, Aaron K. Grant, Benjamin A. Lakin, Brian D. Snyder, and Mark W. Grinstaff
Journal of Orthopaedic Research 2020, 38, 719-725.

322. Synchrotron micro-CT Reveals the Potential of the Dual Contrast Technique for Quantitative Assessment of Human Articular Cartilage Composition.
Miitu K. M. Honkanen, Annina E. A. Saukko, Mikael J. Turunen, Rubina Shaikh, Mithilesh Prakash, Goran Lovric, Antti Joukainen, Heikki Kröger, Mark W. Grinstaff, and Juha Töyräs
Journal of Orthopaedic Research 2020, 38, 563-573.

321. Sustainable Polycarbonate Adhesives for Dry and Aqueous Conditions with Thermo-responsive Properties.
Anjeza Beharaj, Ethan Z. McCaslin, William A. Blessing, and Mark W. Grinstaff
Nature Communications 2019, 10, 5478.

320. From Simple to Architecturally Complex Hydrogel Scaffolds for Cell and Tissue Engineering Applications: Opportunities Presented by Two-photon Polymerization.
Jiaxi Song, Christos Michas, Christopher S. Chen, Alice E. White, and Mark W. Grinstaff
Advanced Healthcare Materials 2019, 1901217.

319. Triple Contrast CT Method Enables Simultaneous Evaluation of Articular Cartilage Composition and Segmentation.
Miitu K.M. Honkanen, Annina E.A, Saukko, Mikael J. Turunen, Wujun Xu, Goran Lovric, Juuso T.J. Honkanen, Mark W. Grinstaff, Vesa-Pekka Lehto, and Juha Töyräs
Annals of Biomedical Engineering 2019, 556–567.

318. Contrast Enhanced Computed Tomography for Real Time Quantification of Glycosamino Glycans in Cartilage Tissue Engineering Constructs.
João P. Garcia, Alessia Longoni, Debby Gawlitta, Antoine J.W.P. Rosenberg, Mark W. Grinstaff, Juha Töyräs, Harrie Weinans, Laura B. Creemers, and Behdad Pouran
Acta Biomaterialia 2019, 100, 202-212.

317. Protocol Development for Synchrotron Contrast-Enhanced CT of the Human Hip.
Honglin Zhang, George Belev, Rachel C. Stewart, Mark W. Grinstaff, Brian D. Snyder, and David R. Wilson
Medical Engineering and Physics 2019, 73, 1-8.

316. A Versatile and Accessible Polymer Coating for Functionalizable Zwitterionic Quantum Dots with High DNA Grafting Efficiency.
Chloé Grazon, Margaret Chern, Katherine Ward, Sébastien Lecommandoux, Mark W. Grinstaff, and Allison M. Dennis
Chemical Communications 2019, 55, 11067-11070.

315. The Cell Adhesion Molecule IGPR-1 is Activated by and Regulates Responses of Endothelial Cells to Shear Stress.
Rachel Xi-Yeen Ho, Rawan Tahboub, Razie Amraei, Jordan Shafran, Rosana D. Meyer, Nitinun Varongchayakul, Mark W. Grinstaff, and Nader Rahimi
Journal of Biological Chemistry 2019, 294, 13671-13680.

314. Biodegradable PLGA Nanoparticles Restore Lysosomal Acidity and Protect Neural PC-12 Cells Against Mitochondrial Toxicity.
Jialiu Zeng, Andrew Martin, Xue Han, Orian S. Shirihai, and Mark W. Grinstaff
Industrial & Engineering Chemistry Research 2019, 58, 13910-13917.

313. Recapitulating Bone Development through Engineered Mesenchymal Condensations and Mechanical Cues for Tissue Regeneration.
Anna M. McDermott, Samuel Herberg, Devon E. Mason, Hope B. Pearson, James H. Dawahare, Joseph M. Collins, Rui Tang, Mark W. Grinstaff, Daniel J. Kelly, Eben Alsberg, and Joel D. Boerckel
Science Translational Medicine 2019, 11, eaav7756.

312. Intra-Articular Injection of Relaxin-2 Alleviates Shoulder Arthrofibrosis.
William A. Blessing, Stephen M. Okajima, M. Belen Cubria, Juan C. Villa-Camacho, Miguel Perez-Viloria, Patrick Williamson, Angie N. Sabogal, Sebastian Suarez, Lay-Hong Ang, Suzanne White, Evelyn Flynn, Edward K. Rodriguez, Mark W. Grinstaff, and Ara Nazarian
Proceedings of the National Academy of Science USA 2019, 116, 12183-12192.

311. Contrast-Enhanced Computed Tomography Scoring System for Distinguishing Early Osteoarthritis Disease States: A Feasibility Study.
Rachel C. Stewart, Brad B. Nelson, Chris E. Kawcak, Jonathan D. Freedman, Brian D. Snyder, Laurie R. Goodrich, and Mark W. Grinstaff.
Journal of Orthopaedic Research 2019, 37, 2138-2148.

310. A Synthetic Bottle-brush Polyelectrolyte Reduces Friction and Wear of Intact and Previously Worn Cartilage.
Benjamin A. Lakin, Benjamin G. Cooper, Luai Zakaria, Daniel J. Grasso, Michel Wathier, Alison M. Bendele, Jonathan D. Freedman, Brian D. Snyder, and Mark W. Grinstaff
ACS Biomaterials Science & Engineering 2019, 5, 3060-3067.

309. Evaluation of Equine Articular Cartilage Degeneration After Mechanical Impact Injury Using Cationic Contrast Enhanced Computed Tomography.
Brad B. Nelson, Janne T. A. Mäkelä, Taylor B. Lawson, Amit N. Patwa, Myra F. Barrett, C. Wayne McIlwraith, Mark B. Hurtig, Brian D. Snyder, Valerie J. Moorman, Mark W. Grinstaff, Laurie R. Goodrich, and Chris E. Kawcak
Osteoarthritis and Cartilage 2019, 27, 1219-1228.

308. Simultaneous Quantitation of Cationic and Non-ionic Contrast Agents in Articular Cartilage Using Synchrotron MicroCT Imaging.
Annina EA Saukko, Mikael J Turunen, Miitu Korhonen, Goran Lovric, Virpi Tiitu, Juuso TJ Honkanen, Mark W Grinstaff, Jukka S Jurvelin, and Juha Töyräs
Nature Scientific Reports 2019, 9, 7118.

307. Imaging of Proteoglycan and Water Contents in Human Articular Cartilage with Full-Body CT Using a Dual Contrast Technique.
Miitu K.M. Honkanen, Hanna Matikka, Juuso T.J. Honkanen, Abhisek Bhattarai, M. W. Grinstaff, Antti Joukainen, Heikki Kröger, Jukka S. Jurvelin, and Juha Töyräs
Journal of Orthopaedic Research 2019, 37, 1059-1070.

306. Design, Synthesis, and Biomedical Applications of Synthetic Sulfated Polysaccharides.
Hannah E. Caputo, Magali Moreau, John E. Straub, and Mark W. Grinstaff
Chemical Society Reviews 2019, 48, 2338–2365.

305. Degradable Nanoparticles Restore Lysosomal pH and Autophagic Flux in Lipotoxic Pancreatic Beta Cells.
Jialiu Zeng, Orian Shirihai, and Mark W. Grinstaff
Advanced Healthcare Materials, "Special Issue entitled Biomaterials for Metabolic Diseases" 2019, 1801511.

304. Meroterpenoids from Neosetophoma sp.: A Dioxa[4.3.3]Propellane Ring System, Potent Cytotoxicity, and Prolific Expression.
Tamam El-Elimat, Huzefa A. Raja, Sloan Ayers, Steven J. Kurina, Joanna E. Burdette, Zachary F. Mattes, Robert C. Sabatelle, Jeffrey W. Bacon, Aaron H. Colby, Mark W. Grinstaff, Cedric J. Pearce, and Nicholas H. Oberlies
Organic Letters 2019, 21, 529-534.

303. SUV39H1 Represses the Expression of Cytotoxic T Lymphocyte Effectors to Promote Colon Tumor Immune Evasion
Chunwan Lu, Dafeng Yang, John D. Klement, Kyu Oh, Natasha M. Savage, Aaron H. Colby, Mark W. Grinstaff, Nicholas H. Oberlies, Cedric Pearce, Thomas Albers, Iryna O. Lebedyeva, and Kebin Liu
Cancer Immunology Research 2019, 7, 414-427.

302. Bioconjugated Oligonucleotides: Recent Developments and Therapeutic Applications
Sebastien Benizri, Arnaud Gissot, Andrew Martin, Brune Vialet, Mark W. Grinstaff , and Philippe Barthélémy
Bioconjugate Chemistry 2019, 30, 366-383.

301. Assessment of Healthy Trapeziometacarpal Cartilage Properties using Indentation Testing and Contrast-enhanced Computed Tomography
Benjamin Dourthe, Reza Nickmanesh, David R. Wilson, Priscilla D'Agostino, Amit N. Patwa, Mark W. Grinstaff, Brian D. Snyder, Faes Kerkhof, G. Harry van Lenthe, and Evie Vereecke
Clinical Biomechanics 2019, 61, 181-189.